CAFs release substantial amounts of growth factors and proinflammatory cytokines, such as transforming growth factor-β (TGF-β), interleukin-6 (IL-6), and CC-chemokine ligand 2 (CCL2), which recruit immune cells, particularly immunosuppressive cells, into the tumor stroma, promoting immune evasion [15,16]. The gene discussed is IL6; the disease is neoplasm.