AFP and hepatocellular carcinoma: For example, AFP can regulate the expression of miR-29, and serum levels of AFP in patients with HCC are significantly correlated with several miRNAs, including miR-451a, miR-483-5p, miR-423-3p, miR-221-3p, let-7b-5p, miR-301a-3p, miR-410, and miR-382-5p [45].