TGFB1 and central nervous system cancer: Further KEGG enrichment analysis demonstrated that these miRNAs predominantly participate in multiple signaling pathways regulating the pluripotency of stem cells, Hippo and Wnt signaling pathways, various cancer-related pathways, synaptic plasticity mechanisms (including long-term depression and potentiation), and neurodegenerative processes such as those observed in glioma and TGF-β signaling (Figure S3J).