The concentrations of anti-inflammatory cytokines IL-4 and IL-10 increased maximally in the subgroups of HER2-positive breast cancer: luminal B(+) (+108.1%, p = 0.0006 and +163.6%, p = 0.0000) and non-luminal (+105.6%, p = 0.0015 and +142.7%, p = 0.0000). The gene discussed is IL4; the disease is breast carcinoma.