These tumor-promoting effects are reported to be, at least in part, mediated by the activation of several key signaling oncogenic pathways such as the phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt) pathway and the mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/ERK) pathway [35,36,38]. This evidence concerns the gene AKT1 and neoplasm.