Numerous studies have examined the genetic association of polymorphisms of VEGF, especially rs10434, rs3025053, rs699947, rs2010963, rs833061, and rs25648, which have been reported to have an effect on miscarriage in women of ethnically diverse groups, but there are no studies that specifically investigate these particular SNPs and their impact on miscarriage in Saudi women. This evidence concerns the gene VEGFA and spontaneous abortion.