In another study, exogenous activation of integrin α5β1, downstream focal adhesion kinase (FAK)/ERK and JUN NH2 terminal kinase (JNK) phosphorylation, and subsequent transcriptional upregulation of VE cadherin (CD144) and MMP2 in U87, and primary glioblastoma cells was shown by Liu et al. [11]. This evidence concerns the gene CDH5 and glioblastoma.