OLIG2 and glioblastoma: Genome-wide CRISPR-Cas9 screening of 10 patient-derived GSCs and two NSCs by Macleod et al. (2019) revealed that despite the diverse molecular alterations of glioblastoma, a core gene set governs both GSC and NSC maintenance and growth including SOX genes, oligodendrocyte transcription factor 2 (OLIG2) and SALL1 [166,167].