IGFBP2 and glioblastoma: This, in combination with analysis of glioblastoma formalin-fixed paraffin-embedded tissue samples identified a nine-gene signature including IGFBP-2, chitinase-3-like protein 1 (CHI3L1)/YKL-40, galectin 3 (LGALS3) and OLIG2 that was predictive of worse clinical outcomes [210].