BMAL1 and acute myocardial infarction: In summary, circadian rhythm oscillations of BMAL1 were significantly enhanced in rats with acute myocardial infarction, and its mediated β3-AR activation decreased the frequency of ventricular tachycardias (VTs) and ventricular fibrillations (VFs) with acute myocardial infarctions or healed myocardial infarctions, reducing the occurrence of adverse cardiac events [42].