The pathways related to infection including staphylococcus aureus infection and pertussis were specifically enriched in the contrast of the Y4.5_S vs. Y0.5_S group, and the pathways related to hormones including thyroid hormone synthesis and the estrogen signaling pathway were specifically enriched when comparing the Y2.5_V vs. Y0.5_V group (Figure 3C). The gene discussed is TG; the disease is staphylococcus aureus infection.