LEP and type 1 diabetes mellitus: BG levels among the groups of mice with IDDM that were treated with leptin alone (LEP group) were significantly lower than those untreated (UNT group) from days 4 to 10, and BG in both of those groups was significantly higher than in the healthy controls (HC, the only group without IDDM) from days 0 to 10 (Figure 1A).