The Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis revealed that the target genes of the miRNAs were primarily associated with the following pathways: long-term potentiation, Hedgehog signaling, renal cell carcinoma, microRNAs in cancer, TGF-β signaling, longevity regulation, endocrine resistance, cellular senescence, axon guidance, oocyte meiosis, thyroid hormone signaling, MAPK signaling, proteoglycans in cancer, focal adhesion, Rap1 signaling, human cytomegalovirus infection, PI3K−Akt signaling, actin cytoskeleton regulation, endocytosis, and general cancer pathways. The gene discussed is TGFB1; the disease is hereditary clear cell renal cell carcinoma.