The data provided reveal significant difference between the serum and urine biomarkers of PT dysfunction (KIM-1, NAG), podocyte damage (synaptopodin, podocalyxin), mitochondrial dysfunction (mtDNA), inflammation (SDF-1), endothelial dysfunction (P-selectin), and oxidative stress (AOPPs). The gene discussed is PODXL; the disease is endothelial dysfunction.