NPPB and atrial fibrillation: RTP was also shown to be more effective than the conventional therapy optimisation sequence, irrespective of sex, age, kidney function, the presence of atrial fibrillation/flutter, underlying HF risk profile, LVEF, SBP, and NT-proBNP, among other factors, based on secondary analyses of the STRONG-HF trial [39,40,41,42,43,44,45].