In our study, when MI prevalence was 13.28%, the NPVs of hs-cTnI and hs-cTnT were nearly identical, with 98.97% (95% CI: 93.57–99.95) for hs-cTnI and 98.51% (95% CI: 90.08–99.92) for hs-cTnT. The gene discussed is TNNT2; the disease is myocardial infarction.