Our study revealed three main findings: (1) the accuracy of the hs-cTnI assay (0.87) to detect true MI was higher compared to hs-cTnT (0.64) in our patient population; (2) the test results for hs-cTnI were available 74 min faster on average compared to hs-cTnT; (3) in CKD patients, hs-cTnT is elevated even without MI, whereas hs-cTnI better differentiates MI from non-MI cases. The gene discussed is TNNI3; the disease is chronic kidney disease.