In the survival submodel, which accounted for time-varying PTH, along with calcium, phosphorus, age ≥65 years, sex, diabetes, hypertension, and medication use, time-varying PTH was significantly associated with an increased risk of IHD (coefficient = 0.001, 95% CI 0.0001–0.002, p = 0.022). This evidence concerns the gene PTH and myocardial ischemia.