The albumin/globulin (A/G) ratio was also lower in the pleural effusion group (median 1.05 vs. 1.16, p = 0.027), while the CRP/albumin (CRP/A) ratio was significantly higher in patients with pleural effusion (2.84 vs. 0.839, p < 0.001). The gene discussed is ALB; the disease is Pleural effusion.