SAMM50 and neoplasm: Among the 65 patients, according to the Ryan regression grade, 81.5% (53) were classified as TRG1 (no tumor or very little tumor with fibrosis throughout the entire wall), 6.2% (4) as TRG2 (fibrosis more predominant than the tumor), and 12.3% (8) as TRG3 (fibrosis less predominant than the tumor).