In this review, SNPs were identified in genes associated with key functional pathways such as muscle structure, function and atrophy, neurotransmission, lipid metabolism and adipogenesis, insulin signaling and glucose metabolism, oxidative stress and inflammation, hormonal regulation, and cell cycle control and tissue regeneration, underscoring the multifaceted genetic architecture underlying sarcopenia and sarcopenic obesity. This evidence concerns the gene INS and sarcopenia.