These include the C-myc oncogene, which drives uncontrolled cell growth; Toll-like receptor 4 (TLR4), involved in immune recognition of microbial components; nuclear factor-kappa B (NF-κB), a transcription factor that regulates inflammation and immune responses; and human telomerase reverse transcriptase (hTERT), an enzyme that maintains telomere length and is often upregulated in cancer cells [9]. The gene discussed is TLR4; the disease is cancer.