AKT1 and amebiasis: In this study, the differential genes EMCN and SYT12 have a fold change of ≥2.00 and Padj ≤ 0.05, and 2145 genes annotated to KEGG are significantly enriched in four pathways: the PI3K-Akt signaling pathway, focal adhesion, amebiasis, and the cancer pathway, in this order.