IRF1 and cancer: The expression of five of these 32 genes (IRF1, IKZF1, SPI1, SH2B3 and LAT) were strongly correlated (Spearman’s ρ > 0.5) with the expression of at least one tumor immune cell infiltrate marker (CD4, CD8A, CD11B and CD45) in all four cancer types (breast, prostate, ovarian and endometrial) in bulk RNA-Seq data from TCGA (Figure 1).