CD4 and inflammatory bowel disease: The ICI analysis revealed that the IBD cohort demonstrated a statistically significant elevation in resting memory CD4+ T cells, M0 macrophages, M1 macrophages, and neutrophils, concurrent with a marked reduction in CD8+ T cells, memory B cells, naïve CD4+ T cells, activated memory CD4+ T cells, γδ T cells, and eosinophils.