Specifically, the IBD group exhibited elevated infiltration of resting CD4+ memory T cells, M0/M1 polarized macrophages, and neutrophils, whereas reduced abundance was observed for CD8+ T cells, memory B cells, naïve CD4+ T cells, activated CD4+ memory T cells, γδ T cells, and eosinophils. The gene discussed is CD8A; the disease is inflammatory bowel disease.