NFKB1 and hematocrit: While NF-kB levels in the euthyroid group were similar to those in the control group and NF-kB levels in the hypothyroid group were similar to HT with TRT, NF-kB levels were significantly higher in both HT with TRT and hypothyroid HT without TRT compared to control and euthyroid HT without TRT (Figure 1A).