After adjusting for US-FLI, sex, EF, T2DM, HBP, TBIL, ApoA1, and physical activity, it was discovered that US-FLI and the risk of CAD were positively associated (OR = 1.262, 95% CI: 1.025–1.553, p = 0.028), and T2DM (OR = 3.337, 95% CI: 1.226–9.085, p = 0.018) was identified as an independent risk factor for patients in the intermediate-risk group (Table 5). The gene discussed is APOA1; the disease is coronary artery disorder.