Cecconi et al. [40] reported that leukocytosis [white blood cell count > 10×109/L], lymphocytopenia (lymphocyte count < 1 × 109/L), and elevated levels of certain laboratory parameters such as procalcitonin, interleukin-6, serum ferritin, C-reactive protein, aspartate aminotransferase, serum creatinine, lactate dehydrogenase, fibrinogen, troponin-I, and D-Dimer were statistically significant predictors of clinical deterioration leading to ICU admission or death in hospitalized COVID-19 patients. The gene discussed is IL6; the disease is Increased total leukocyte count.