HMOX1 and macular degeneration: Nrf2, Heme Oxygenase-1 (HO-1), Antioxidant, Anti-inflammatory, Detoxification, Aging, Neurodegeneration, Macular Degeneration, Stress Protection, Longevity, Transcription Factors, Cytoprotection, Apoptosis, Angiogenesis, Age-dependent Disorders