Molecular pathology also plays an important role in the classification and prognosis of gliomas, with common molecular markers that include isocitrate dehydrogenase (IDH) 1/2, O6-methylguanine-DNA methyltransferase (MGMT) gene promoter methylation, loss of alpha thalassemia/mental retardation syndrome x-linked (ATRX), tumor protein (TP) 53 mutations, and complete deletion of both the short arm of chromosome 1 (1p) and the long arm of chromosome 19 (19q) [3]. The gene discussed is MGMT; the disease is glioma.