CYP2D6 and cancer: As a potent CYP2D6 inhibitor, numerous interactions with drugs metabolized via this enzyme are possible, including beta-blockers (atenolol, bisoprolol, and metoprolol), antiarrhythmics (amiodarone), antihypertensives (clonidine), antipsychotics (risperidone and haloperidol), other antidepressants (citalopram, escitalopram, and amitriptyline), and cancer drugs (tamoxifen) [45].