Li et al. [99] demonstrated that the ferroptosis inducers erastin and sorafenib effectively triggered ferroptosis in N5CP cells by modulating the expression of NRF2 or xCT, leading to excessive accumulation of intracellular lipid ROS, thereby altering the sensitivity of NSCLC cells to CDDP. The gene discussed is SLC7A11; the disease is non-small cell lung carcinoma.