Notably, the expression of SNHG16 is significantly elevated in liver cancer tissues and cell lines, where it exerts oncogenic effects through pathways such as miR-17-5p/p62, miR-4500/STAT3, and miR-605-3p/TRAF6/NF-κB [29,30,31]. The gene discussed is NFKB1; the disease is liver cancer.