Following previous findings, Caspase 3/7 activity was increased following 24 h Met- conditions in only PC3 wt and AMPK−/− PCa cells (Figure 6a, ** p = 0.0023, control vs. Met- in wt PC3 cells; *** p = 0.0010, control vs. Met- in AMPK−/− PC3 cells). This evidence concerns the gene CASP3 and posterior cortical atrophy.