Lastly, GO analysis revealed key MFs for the OT compounds targeting the downregulated genes of different BC subtypes through insulin receptor substrate binding for LaBCxOT, nitric oxide synthase regulator activity for LbBCxOT, protein serine/threonine/tyrosine kinase activity for Her2xOT, and cyclin-dependent protein serine/threonine kinase activity for TNBCxOT. This evidence concerns the gene INSR and breast cancer.