Phosphorylation-regulated SNAP-23 promotes the release of tumor exosomes by facilitating stable complex formation [209], and the down-regulation of O-GlcNAclation transferase enhances exosome secretion via facilitating the formation of the SNAP-23-Stx4-VAMP8 complex that increases efflux of intracellular cisplatin [210]. Here, SNAP23 is linked to neoplasm.