Serum samples of 112 patients with AD were compared to samples of 101 healthy control patients, and the protein levels of NF-κB, oxidative stress indices, and apoptosis regulators, as well as pyroptosis markers (NLRP3, caspase-1, and IL1β) were measured along with their mRNA expression levels [33]. This evidence concerns the gene NFKB1 and Alzheimer disease.