Salvianolic acid B, derived from Salvia miltiorrhiza, exhibits anti-inflammatory properties by modulating macrophage polarization, switching macrophages from the M1 (pro-inflammatory) phenotype to the M2 (anti-inflammatory) phenotype, effectively reducing NLRP3 inflammasome activation and illustrating the potential of natural compounds in combating AD [57]. Here, NLRP3 is linked to Alzheimer disease.