CXCL12 and breast neoplasm: Similarly, TA was found to specifically inhibit CXC motif chemokine 12 (CXCL12)-induced migration of human monocytes as well as CXCL12 binding to THP-1 cells and CXCL12-induced migration of MDA-231 breast tumor cells in vitro, providing a possible underlying mechanism for its reported anti-inflammatory activity [40].