The CXCL5-Fc and CXCL1-Fc fusion proteins showed greater binding than the native chemokines to THP-1 cells (Figure 4B), which are acute myeloid leukemia (AML) cells of myeloid origin and CXCR2-positive (Figure S3A). This evidence concerns the gene CXCL1 and acute myeloid leukemia.