In K562 leukaemia cells, HSP induced apoptosis, arrested the G0/G1 phase, and increased the expression of the DUSP1 (dual specificity phosphatase 1), DUSP3, DUSP5, CDK1A, CDK1B, GADD45B, SPRR2D, MT1F, MT1A, p27Kip1, CASP4, and NFKBIA genes [170]. The gene discussed is DUSP1; the disease is leukemia.