These findings align with the idea that alterations during the early developmental stages of astrocytic progenitors (such as the impaired expression of D-serine synthesis and the downregulation of glutamate transporters, GLAST) may contribute to non-canonical degenerative processes, thereby exacerbating not only the occurrence of early-stage symptoms due to aberrant pruning processes but also the symptomatology characteristic of the chronic stages of schizophrenia. This evidence concerns the gene SLC1A3 and schizophrenia.