A reduction in GSK3β Ser9 phosphorylation and decrease in β-catenin levels as well as EMT-related Wnt target genes in response to the compound were found in a separate study in HepG2 hepatocellular carcinoma [124] and in A2780 and SK-OV-3 epithelial ovarian cancer lines, inhibiting EMT in these lines [116]. The gene discussed is GSK3B; the disease is hepatocellular carcinoma.