Several compounds of this type are reported in only one study, such as ophiopogonin B, which was tested using non-small-cell lung carcinoma cell lines, causing a reduction in β-catenin levels in both the cytoplasm and nucleus, as well as the Wnt target genes cyclin D1 and c-Myc, which, in turn, led to a reduction in cell migration and invasion. Here, CCND1 is linked to small cell lung carcinoma.