In this way, the compound suppressed the epithelial–mesenchymal transition, which was also partly achieved through direct ROS scavenging activity and associated carcinogenic properties of hepatocellular carcinoma Huh7 and MHCC97-H cells, which was caused by controlling the phosphorylating activity of AKT via Ser9 in GSK3β, as confirmed by the finding that the AKT inhibitor GSK690693 was effective in suppressing it [100]. Here, AKT1 is linked to hepatocellular carcinoma.