The mRNA levels of NRF2 (Figure 3B), as well as Glutamate–Cysteine Ligase Catalytic subunit (GCLC) (Figure 3C) and Glutathione Reductase (GSR) (Figure 3D), were lower in the PCOS group, demonstrating that the NRF2-derived antioxidant response was impaired among our women with PCOS. This evidence concerns the gene GSR and polycystic ovary syndrome.