The mRNA levels of NRF2 (Figure 3B), as well as Glutamate–Cysteine Ligase Catalytic subunit (GCLC) (Figure 3C) and Glutathione Reductase (GSR) (Figure 3D), were lower in the PCOS group, demonstrating that the NRF2-derived antioxidant response was impaired among our women with PCOS. The gene discussed is GCLC; the disease is polycystic ovary syndrome.