This study assessed the changes in mRNA expression (Figure 4A) and protein levels (Figure 4B,C) of inflammatory factors (NLRP3, ASC, Caspase-1, and IL-1β) in various groups in order to determine whether APS affects the NLRP3 pathway (with decreased expression) and ultimately lessens the degree of cellular EMT. The gene discussed is PYCARD; the disease is autoimmune polyendocrinopathy.