The GFCT’s community-based PSA testing program (https://gfct.mypsatests.org.uk/ (accessed on 15 April 2025)) has achieved widespread uptake and addresses a significant gap in prostate cancer testing in the UK, as evidenced by the distribution of postcodes of men who underwent PSA testing organised by the GFCT. Here, KLK3 is linked to Familial prostate cancer.