BRCA1 and breast carcinoma: However, when stratifying according to the form of breast cancer presentation, we found in patients with mutated BRCA1/2 mutation a significant increase in the plasma levels of resolvins D1 and D2 (median Δ%T0-T1: +185.8 and +101.2, respectively) (p = 0.037 and p = 0.028).