An increased risk of melanoma was not found by Li et al. [25] in their large study, which included 7376 female BRCA1 GPV carriers [RR 0.80, 95%CI 0.13–5.06] and 5032 female BRCA2 GPV carriers [RR 1.82, 95%CI 0.43–7.71]. This evidence concerns the gene BRCA1 and melanoma.