The 60-year age limit of this study may explain this difference in findings in small part, although Li et al. found an increased risk of pancreatic cancer in female BRCA2 GPV carriers under the age of 65 years [RR = 4.92 [95%CI 2.96–7.80] for age < 65 years and 1.77 [95%CI, 0.87 to 3.58] for age ≥ 65 years]. Here, BRCA2 is linked to pancreatic neoplasm.