In mice with murine colon carcinoma, it induces the accumulation of T helper type 17 (Th17) cells in tumor-draining lymph nodes [122], which increases the expression of macrophage inflammatory protein-2 (MIP-2) (but not keratinocyte-derived chemokine (KC)) that causes the infiltration of neutrophils into tumor-draining lymph nodes. The gene discussed is CALCA; the disease is neoplasm.