The cancer surgery only subgroup analysis included seven studies [23,24,30,31,32,33,41], and the TNF-α levels was significantly lower in EA cohort (SMD = −0.89, 95% CI = −1.47 to −0.32, I2 = 89%, Egger’s regression p = 0.05, trim and fill reported no missing studies, Supplementary Figure S2). The gene discussed is TNF; the disease is cancer.