ELAVL1 and familial pancreatic carcinoma: However, a retrospective study conducted in a cohort of 175 patients with resected periampullary adenocarcinomas, including pancreatic cancer, could not confirm the association between HuR and DCK expression and found that high HuR levels or a high HuR cytoplasmic-to-nuclear ratio is associated with poor survival in patients that received gemcitabine [133].