Zheng and colleagues found changes in the sera of AL patients compared to the sera of healthy donors: decreased levels of α1-trypsin inhibitor, trypsin inhibitor, prealbumin and apolipoproteins E and A-IV, as well as increased levels of retinol-binding protein, globin HP2, serum lectin, factor H protein homolog and A1 amyloid [25]. The gene discussed is TTR; the disease is axial length measurement.