These results are in agreement with previous phenotypic characterizations of VHL-related hemangioblastomas [19,52,53], which identified three main cell types: stromal cells, the most abundant and which would be essential for tumor growth; pericytes, which would contribute to vascular stability; and endothelial cells, which, although less numerous, could play a crucial role in vessel formation in these highly vascularized tumors. The gene discussed is VHL; the disease is hemangioblastoma.