Of these 13, 10 showed no prior evidence of direct association with DKD based on a systematic search of PubMed, GWAS Catalog [31], Open Targets [32], and ClinVar [33], and are thus considered previously unreported susceptibility genes, including MSH5, PHTF1, PRRT1, ZSCAN9, ZNF165, ZKSCAN8, MICB, VWA7, POU5F1, and CYP21A2. The gene discussed is MSH5; the disease is diabetic kidney disease.