Ten genes (MSH5, PHTF1, PRRT1, ZSCAN9, ZNF165, ZKSCAN8, MICB, VWA7, POU5F1, and CYP21A2) showed no prior association with DKD in systematic searches of PubMed, GWAS Catalog [31], Open Targets [32], and ClinVar [33] databases, representing novel susceptibility candidates. The gene discussed is CYP21A2; the disease is diabetic kidney disease.